Necrotizing Sarcoid Granulomatosis: Ocular Manifestation in 3 Children of African Origin

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Necrotizing sarcoid granulomatosis: ocular manifestation in 3 children of African origin.

Necrotizing sarcoid granulomatosis (NSG) is a rare systemic disease characterized by confluent sarcoidlike granulomas with necrotic areas and a variable degree of vasculitis. First described by Liebow in 1973, NSG can be classified as a disease showing features of Wegener granulomatosis and sarcoidosis. The etiology and pathogenesis of NSG are so far unknown; it is considered to be unrelated to...

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Necrotizing sarcoid granulomatosis.

Twelve cases of necrotizing sarcoid granulomatosis are presented as a retrospective study. The population of patients consisted of ten women and two men, with an average age of 50 years. Nine patients initially had a variety of pulmonary and nonpulmonary complaints, while three were asymptomatic. Chest roentgenograms demonstrated bilateral nodules in seven patients, solitary nodules in four, an...

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Necrotizing sarcoid granulomatosis with extrapulmonary involvement.

Pulmonary lesions, with sarcoid-like granulomas exhibiting noncaseous necrosis, with associated granulomatous arteritis fulfil the diagnostic criteria of necrotizing sarcoid granulomatosis (NSG). We report the case of a woman who presented with recurrent headaches, transient right hemipareses and left-sided ophthalmoplegia. An excised left retro-orbital lesion demonstrated sarcoid like changes,...

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Necrotizing sarcoid granulomatosis with an uncommon manifestation: clinicopathological features and review of literature.

We report a rare case of an incidental diagnosis of necrotizing sarcoid granulomatosis (NSG) in a 60-y-old non-smoking male. The patient was admitted to the hospital for sudden back pain. Chest x-ray revealed areas of parenchymal consolidation and high-resolution computed tomography demonstrated a pulmonary nodular pattern with no lymph node enlargement. All laboratory and pulmonary function te...

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A case of a 14-yr-old female with necrotizing sarcoid granulomatosis (NSG) is presented. She was referred because of chest pain and malaise, and radiography revealed multiple pulmonary nodules. Her history showed seasonal sensitization to aeroallergens and hay fever. Infectious agents or malignancies did not characterize these nodules. However, she was treated with macrolide antibiotics because...

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ژورنال

عنوان ژورنال: Archives of Ophthalmology

سال: 2011

ISSN: 0003-9950

DOI: 10.1001/archophthalmol.2011.281